Placental Hypomethylation Is More Pronounced in Genomic Loci Devoid of Retroelements


The human placenta is hypomethylated compared to somatic tissues. However, the degree and specificity of placental hypomethylation across the genome is unclear. We assessed genome-wide methylation of the human placenta and compared it to that of the neutrophil, a representative homogeneous somatic cell. We observed global hypomethylation in placenta… (More)
DOI: 10.1534/g3.116.030379