Placental DNA hypomethylation in association with particulate air pollution in early life

Abstract

There is evidence that altered DNA methylation is an important epigenetic mechanism in prenatal programming and that developmental periods are sensitive to environmental stressors. We hypothesized that exposure to fine particles (PM2.5) during pregnancy could influence DNA methylation patterns of the placenta. In the ENVIRON AGE birth cohort, levels of 5… (More)
DOI: 10.1186/1743-8977-10-22

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