Placenta growth factor is induced in human keratinocytes during wound healing.

@article{Failla2000PlacentaGF,
  title={Placenta growth factor is induced in human keratinocytes during wound healing.},
  author={Cristina M Failla and Teresa Odorisio and Francesca Cianfarani and Cataldo Schietroma and Pietro Puddu and Giovanna Zambruno},
  journal={The Journal of investigative dermatology},
  year={2000},
  volume={115 3},
  pages={388-95}
}
Placenta growth factor (PlGF) is a dimeric glycoprotein, structurally and functionally related to the vascular endothelial growth factor, a potent angiogenic/permeability factor known to play a role in the neoangiogenesis during wound repair. In this study we evaluated the expression of PlGF in human keratinocytes and investigated its possible role in wound healing. Northern blot analysis on cultured keratinocytes revealed a 1.7 kb mRNA transcript and reverse transcriptase-polymerase chain… CONTINUE READING