Placenta growth factor expression in human atherosclerotic carotid plaques is related to plaque destabilization.

BACKGROUND AND PURPOSE Placenta growth factor (PlGF) mediates angiogenesis and inflammation, but its role in human atherosclerosis is unknown. This study was designed to test the hypothesis that PlGF-expression in human atherosclerotic carotid plaques is related to inflammation, vascularization and clinical plaque instability. METHODS The expression of… (More)