Placebos in clinical practice and research.

  title={Placebos in clinical practice and research.},
  author={Peter Paul De Deyn and Rudi D'hooge},
  journal={Journal of medical ethics},
  volume={22 3},
The main current application of placebo is in clinical research. The term placebo effect refers to diverse non-specific, desired or non-desired effects of substances or procedures and interactions between patient and therapist. Unpredictability of the placebo effect necessitates placebo-controlled designs for most trials. Therapeutic and diagnostic use of placebo is ethically acceptable only in few well-defined cases. While "therapeutic" application of placebo almost invariably implies… CONTINUE READING

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