Placebo effect and randomized clinical trials

  title={Placebo effect and randomized clinical trials},
  author={G. Elander and G. Hermer{\'e}n},
  journal={Theoretical Medicine},
The achievement of optimal therapeutic results presupposes the use of appropriate treatment combined with maximal utilization of placebo effects. These aims may sometimes be difficult to satisfy in randomized clinical trials (RCTs). The question thus arises whether there is a conflict between the goals of therapy and those of experimental research; and if so, to what extent, and how is it handled in practice by clinicians and researchers. Various ethical problems have been discussed in several… Expand

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