Placebo-controlled trials in psychiatric research: an ethical perspective.

@article{Miller2000PlacebocontrolledTI,
  title={Placebo-controlled trials in psychiatric research: an ethical perspective.},
  author={Franklin G. Miller},
  journal={Biological psychiatry},
  year={2000},
  volume={47 8},
  pages={707-16}
}
The placebo-controlled trial is widely regarded as the gold standard for testing the efficacy of new treatments; however, this research design is subject to ethical controversy, especially when standard treatments of proven efficacy exist. After examining regulatory standards and ethical codes relevant to placebo-controlled trials, I offer a critique of arguments against the use of placebo control groups in psychiatric research. An absolute ethical prohibition of placebo-controlled trials in… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

The Meeting of Psychiatry and Humanities: An Overview

Journal of medical ethics and history of medicine • 2009
View 4 Excerpts
Highly Influenced

Introduction: case studies in the ethics of mental health research.

The Journal of nervous and mental disease • 2012
View 2 Excerpts

Clinical equipoise and the incoherence of research ethics.

The Journal of medicine and philosophy • 2007
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 39 references

The continuing unethical use of placebo controls.

The New England journal of medicine • 1994
View 5 Excerpts
Highly Influenced

The Powerful Placebo

AK Shapiro, E Shapiro
1997
View 3 Excerpts
Highly Influenced

Independent capacity assessment : A critique

FG Miller, DL Rosenstein
BioLaw • 1999
View 1 Excerpt

Independent capacity assessment: A critique. BioLaw 11:S432–S439

FG Miller, DL Rosenstein
1999
View 1 Excerpt

Issues in clinical research design: Principles, practices, and controversies

JA Lieberman, S Stroup, +3 authors AJ Rush
1999
View 1 Excerpt

New requirements for manuscripts submitted to Biological Psychiatry: Informed consent and protection of subjects

DS Charney, RB Innis, EJ Nestler
Biol Psychiatry • 1999
View 1 Excerpt

Similar Papers

Loading similar papers…