Placebo-controlled trials in psychiatric research: an ethical perspective.

  title={Placebo-controlled trials in psychiatric research: an ethical perspective.},
  author={Franklin G. Miller},
  journal={Biological psychiatry},
  volume={47 8},
The placebo-controlled trial is widely regarded as the gold standard for testing the efficacy of new treatments; however, this research design is subject to ethical controversy, especially when standard treatments of proven efficacy exist. After examining regulatory standards and ethical codes relevant to placebo-controlled trials, I offer a critique of arguments against the use of placebo control groups in psychiatric research. An absolute ethical prohibition of placebo-controlled trials in… CONTINUE READING

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