Placebo-controlled trial of oral 5-ASA in relapse prevention of Crohn's disease

  title={Placebo-controlled trial of oral 5-ASA in relapse prevention of Crohn's disease},
  author={Dr. Corrado Brignola and Primiano Iannone and Stefano Pasquali and Massimo Campieri and Paolo Gionchetti and Andrea Belluzzi and Oreste Basso and Mario Miglioli and Luigi Barbara},
  journal={Digestive Diseases and Sciences},
Treatment of Crohn's disease (CD) in clinical remission is still a debated issue. Previous studies have shown a high risk of relapse for patients with CD in clinical remission (CDAI<150) but with some abnormally high laboratory parameters as well as a possible beneficial role of low-dosage steroid treatment in this group of patients. Furthermore, good results have been reported on the efficacy of 5-aminosalicylic acid (5-ASA) in moderately active CD. In our study we verified the efficacy of a… CONTINUE READING

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