Placebo controlled study showing therapeutic benefit of iloprost in the treatment of Raynaud's phenomenon.

@article{Kyle1992PlaceboCS,
  title={Placebo controlled study showing therapeutic benefit of iloprost in the treatment of Raynaud's phenomenon.},
  author={M. V. Kyle and Glyn Belcher and Brian L. Hazleman},
  journal={The Journal of rheumatology},
  year={1992},
  volume={19 9},
  pages={1403-6}
}
Iloprost is a chemically stable analog of prostaglandin I2 showing the same properties as the naturally occurring substance, but with advantages of ease of handling and administration to patients. A double blind within patient comparison of intravenous iloprost and placebo was undertaken in 13 patients with Raynaud's phenomenon severe enough to warrant short term hospitalization for intravenous dilator therapy; thermography was used as one form of assessment. Our results, while showing… CONTINUE READING