• Corpus ID: 51962225

Placebo controlled study on Comparison of effects of Nigella Sativa and Nicotinic Acid along with Low Fat Diet and Physical Exercise on LDL-Cholesterol and HDL-Cholesterol

@inproceedings{MoeenudDin2016PlaceboCS,
  title={Placebo controlled study on Comparison of effects of Nigella Sativa and Nicotinic Acid along with Low Fat Diet and Physical Exercise on LDL-Cholesterol and HDL-Cholesterol},
  author={Hafiz Moeen-ud-Din and Shah Murad and Ajaz Fatima},
  year={2016}
}
To get good compliance of therapeutic goal of hypolipidemic agents by cardiologist and patient, some herbal drugs have had been used by some expert cardiologists. Among those herbal medicines Kalonji is most important drug used as hypolipidemic agent. In this research work hypolipidemic effects of kalonji are compared with hypolipidemic effects of Niacin. It was single blind placebo-controlled comparative study, conducted at Jinnah Hospital, Lahore from September 2013 to December 2013. Ninety… 
Effects of Nigella sativa on glycemic control, lipid profiles, and biomarkers of inflammatory and oxidative stress: A systematic review and meta‐analysis of randomized controlled clinical trials
TLDR
This meta‐analysis demonstrated the beneficial effects of N. sativa on fasting glucose, HbA1c, triglycerides, total‐, VLDL‐, LDL‐cholesterol levels.
Effect of low caloric diet supplemented by fennel (Foeniculum vulgare) seeds or black cumin (Nigella sativa) seeds and its mixture on obese adult female patients
The present work was carried out to study the effect of low caloric diet supplemented with fennel seeds or black cumin seeds and their mixture on obese adult females. The control group (G1) used low
Cardiovascular Effects of Nigella Sativa L. and its Constituents
TLDR
This review indicated that Nigella sativa and thymoquinone exhibited beneficial cardiovascular effects on cardiotoxicity, hypertension, hyperlipidemia, and atherosclerosis, probably due to the antioxidant and antiinflammatory properties of Nigella sitiva.
Review on Clinical Trials of Black Seed (Nigella sativa ) and Its Active Constituent, Thymoquinone
TLDR
Some effects of N. sativa, such as its hypoglycemic, hypolipidemic and bronchodilatory effects, have been sufficiently studied and are sufficiently understood to allow for the next phase of clinical trials or drug developments.

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Despite improvement in lipid and lipoprotein concentrations, nicotinic acid must be used with caution in patients with non-insulin-dependent diabetes mellitus with dyslipidemia, because of worsening hyperglycemia and the development of hyperuricemia.
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TLDR
Correcting low HDL-cholesterol in statin-treated patients may provide a means to achieve the next leap forward in the management of cardiovascular disease.
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Compared to a low-fat weight loss diet, a short-term very low-carbohydrate diet did not lower LDL-C but did prevent the decline in HDL-C and resulted in improved insulin sensitivity in overweight and obese, but otherwise healthy women.
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SUMMARY Reduction of low-density lipoprotein cholesterol (LDL-C) is presently the primary focus of lipid-lowering therapy for prevention and treatment of coronary heart disease (CHD). However, the
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