Placebo-controlled randomized clinical trial of fish oil’s impact on fatigue, quality of life, and disease activity in Systemic Lupus Erythematosus

@inproceedings{Arriens2015PlacebocontrolledRC,
  title={Placebo-controlled randomized clinical trial of fish oil’s impact on fatigue, quality of life, and disease activity in Systemic Lupus Erythematosus},
  author={Cristina Arriens and Linda S. Hynan and Robert H. Lerman and David R. Karp and Chandra Mohan},
  booktitle={Nutrition journal},
  year={2015}
}
INTRODUCTION A recent metabolomic screen of sera from patients with Systemic Lupus Erythematosus (SLE) found reduction of antioxidants and substrates for energy generation. These metabolic alterations may underlie one of the most common features of SLE--fatigue. The metabolomic studies also noted reduced omega-3 fatty acids, which are powerful anti- oxidants. This deficiency may be causally related to oxidative stress, inflammation, disease activity, and fatigue in SLE. Supplementation of omega… CONTINUE READING
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