Placebo-controlled comparison of danazol and high-dose medroxyprogesterone acetate in the treatment of endometriosis after conservative surgery.

@article{Telimaa1987PlacebocontrolledCO,
  title={Placebo-controlled comparison of danazol and high-dose medroxyprogesterone acetate in the treatment of endometriosis after conservative surgery.},
  author={S Telimaa and Lars R{\"o}nnberg and Antti Kauppila},
  journal={Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology},
  year={1987},
  volume={1 4},
  pages={363-71}
}
To evaluate the clinical value of postoperative hormone therapy in endometriosis, 60 patients with advanced disease were randomized to receive in a double-blind study danazol (200 mg, 3 times daily), medroxyprogesterone acetate (MPA) (100 mg daily) or placebo post-operatively for 6 months. Treatment efficacy was evaluated clinically and at laparoscopy 6 months after medication. In relation to placebo, danazol and high-dose MPA treatments, which did not differ from each other in efficacy… CONTINUE READING

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