Placebo and endogenous mechanisms of analgesia.

  title={Placebo and endogenous mechanisms of analgesia.},
  author={Fabrizio Benedetti},
  journal={Handbook of experimental pharmacology},
The discovery of the endogenous systems of analgesia has produced a large amount of research aimed at investigating their biochemical and neurophysiological mechanisms and their neuroanatomical localization. Nevertheless, the neurobiological acquisitions on these mechanisms have not been paralleled by behavioural correlates in humans--in other words, by the understanding of when and how these endogenous mechanisms of analgesia are activated. Until recent times one of the most studied… CONTINUE READING