Placebo Orthodoxy in Clinical Research I: Empirical and Methodological Myths

@article{Freedman1996PlaceboOI,
  title={Placebo Orthodoxy in Clinical Research I: Empirical and Methodological Myths},
  author={Benjamin Freedman and Charles Weijer and Kathleen Cranley Glass},
  journal={The Journal of Law, Medicine \& Ethics},
  year={1996},
  volume={24},
  pages={243 - 251}
}
he use of statistics in medical research has been compared to a religion: it has its high priests (statistiT cians), supplicants (journal editors and researchers), and orthodoxy (for example, p < .05 is “significant”).’ Although the comparison may be more unfair to religion than to research, a useful lesson can nonetheless be drawn: the practice of clinical research may benef i tas does the spirit-from critical self-examination. Arguably, no aspect of the conduct of clinical trials is currently… Expand

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