Place navigation impaired in rats with hippocampal lesions

@article{Morris1982PlaceNI,
  title={Place navigation impaired in rats with hippocampal lesions},
  author={R. Morris and P. Garrud and J. Rawlins and J. O'Keefe},
  journal={Nature},
  year={1982},
  volume={297},
  pages={681-683}
}
Electrophysiological studies have shown that single cells in the hippocampus respond during spatial learning and exploration1–4, some firing only when animals enter specific and restricted areas of a familiar environment. Deficits in spatial learning and memory are found after lesions of the hippocampus and its extrinsic fibre connections5,6 following damage to the medial septal nucleus which successfully disrupts the hippocampal theta rhythm7, and in senescent rats which also show a correlated… Expand
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