Pix Proteins and the Evolution of Centrioles

  title={Pix Proteins and the Evolution of Centrioles},
  author={Hugh R. Woodland and Andrew M Fry},
  journal={PLoS ONE},
  pages={574 - 589}
We have made a wide phylogenetic survey of Pix proteins, which are constituents of vertebrate centrioles in most eukaryotes. We have also surveyed the presence and structure of flagella or cilia and centrioles in these organisms, as far as is possible from published information. We find that Pix proteins are present in a vast range of eukaryotes, but not all. Where centrioles are absent so are Pix proteins. If one considers the maintenance of Pix proteins over evolutionary time scales, our… CONTINUE READING

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