Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse.

Abstract

The T-box transcription factor eomesodermin (Eomes) has been implicated as an important component in germ layer induction and patterning in vertebrate embryos. In the mouse, Eomes is essential for development of the trophectoderm lineage and Eomes loss-of-function mutants arrest at implantation. Here, we have used a novel Eomes conditional allele to test… (More)
DOI: 10.1242/dev.014357

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@article{Arnold2008PivotalRF, title={Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse.}, author={Sebastian J Arnold and U. Hofmann and Elizabeth K. Bikoff and Elizabeth J Robertson}, journal={Development}, year={2008}, volume={135 3}, pages={501-11} }