Pivotal role for monocytes/macrophages and dendritic cells in maternal immune response to the developing embryo in cattle.

@article{MansouriAttia2012PivotalRF,
  title={Pivotal role for monocytes/macrophages and dendritic cells in maternal immune response to the developing embryo in cattle.},
  author={Nadera Mansouri-Attia and Lilian de Jesus de Oliveira and Niamh E. Forde and Alan G. Fahey and John A. Browne and James F. Roche and O. Sandra and Pierrette Reinaud and Patrick Lonergan and Trudee Fair},
  journal={Biology of reproduction},
  year={2012},
  volume={87 5},
  pages={123}
}
In mammals, successful pregnancy is dependent in part on the adaptation or regulation of the maternal immune system to prevent the rejection of the embryonic semiallograft. A modification in Th cell function and secretion is a requirement for the establishment and maintenance of pregnancy. Although there is strong evidence from studies in humans and mice linking successful pregnancy with the predominance of Th2-type immunity, the situation in cattle remains unclear. This study describes the… CONTINUE READING

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