Pivotal efficacy trials of inhaled corticosteroids in asthma.

  title={Pivotal efficacy trials of inhaled corticosteroids in asthma.},
  author={Ronina A. Covar},
  journal={Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology},
  volume={117 6},
BACKGROUND Inhaled corticosteroids (ICSs) are the mainstay of daily controller treatment for persistent and uncontrolled asthma. However, many clinicians are wary of ICSs because of safety concerns. Clinicians need to know the underlying efficacy data that support the use of ICSs to weigh efficacy against safety. OBJECTIVE To discuss efficacy data from pivotal trials to aid clinicians in their decisions to use ICSs. METHODS Key efficacy studies were selected to augment discussion. RESULTS… CONTINUE READING