Pivotal Role of KARAP/DAP12 Adaptor Molecule in the Natural Killer Cell–mediated Resistance to Murine Cytomegalovirus Infection

@article{Sjlin2002PivotalRO,
  title={Pivotal Role of KARAP/DAP12 Adaptor Molecule in the Natural Killer Cell–mediated Resistance to Murine Cytomegalovirus Infection},
  author={Hanna Sj{\"o}lin and Elena Tomasello and Mehrdad Mousavi-Jazi and Armando Bartolazzi and Klas K{\"a}rre and Eric Vivier and Cristina Cerboni},
  journal={The Journal of Experimental Medicine},
  year={2002},
  volume={195},
  pages={825 - 834}
}
Natural killer (NK) cells are major contributors to early defense against infections. Their effector functions are controlled by a balance between activating and inhibiting signals. To date, however, the involvement of NK cell activating receptors and signaling pathways in the defense against pathogens has not been extensively investigated. In mice, several… CONTINUE READING