Pivmecillinam in the treatment of urinary tract infections.

  title={Pivmecillinam in the treatment of urinary tract infections.},
  author={Lindsay E. Nicolle},
  journal={The Journal of antimicrobial chemotherapy},
  volume={46 Suppl 1},
  pages={35-9; discussion 63-5}
The efficacy of pivmecillinam for empirical treatment of acute uncomplicated urinary tract infection (UTI) was initially reported in clinical trials published in the 1970s and 1980s. Bacteriological cure rates observed in these trials were consistently >85%, and studies of different dosing regimens suggested that a 3 day course was appropriate. Comparative studies reported that pivmecillinam was equivalent to other antimicrobial agents in terms of clinical and bacteriological outcomes. These… CONTINUE READING
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