Pityriasis rosea

@article{Eisman2015PityriasisR,
  title={Pityriasis rosea},
  author={Samantha Eisman and Rodney Sinclair},
  journal={BMJ : British Medical Journal},
  year={2015},
  volume={351}
}
The cause of pityriasis rosea is uncertain but epidemiological (seasonal variation and clustering in communities) and clinical features suggest an infective agent. Light and electron microscopy findings suggest infectionwith human herpesviruses 6 and 7 (HHV-6/7). These viral antigens have been detected in skin lesions by immunohistochemistry and their DNA has been isolated from non-lesional skin, peripheral blood mononuclear cells, serum, and saliva samples. HHV-6 and HHV-7may also interact… 

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The efficacy of oral acyclovir during early course of pityriasis rosea: a systematic review and meta-analysis

TLDR
Oral acyClovir may be a relatively safe and effective treatment in the early course of PR, and patients with PR may achieve faster symptoms control with acyclovir.

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References

SHOWING 1-10 OF 16 REFERENCES

Pityriasis rosea--an update.

TLDR
In managing a patient with PR, it should concentrate more on how the eruption is affecting the quality of life, rather than the extent and severity of the eruption, i.e. the illness, ratherthan the extent of the illness.

Pityriasis rosea and pityriasis rosea-like eruptions.

Multiple Recurrences in Pityriasis Rosea - A Case Report with Review of the Literature

TLDR
A case of pityriasis rosea is reported in an 11-years-old male with three episodes with review of the literature, and no predisposing factors identified.

Pityriasis rosea is associated with systemic active infection with both human herpesvirus-7 and human herpesvirus-6.

TLDR
The results suggest that pityriasis rosea is associated with systemic active infection with both human herpesvirus-7 and human herpes virus-6, and in situ hybridization enabled detection of human HSV-6 in skin and other tissues isolated from patients with pityriases rosea.

Atypical presentations of pityriasis rosea: case presentations

  • A. ChuhV. ZawarA. Lee
  • Medicine
    Journal of the European Academy of Dermatology and Venereology : JEADV
  • 2005
TLDR
It is believed that it is difficult to make a clear division to define typical and atypical PR, and it is important not to ascribe any unusual or atypicals skin eruption with PR unless other dermatoses have been excluded.

Interventions for pityriasis rosea.

TLDR
There is inadequate evidence for efficacy for most treatments for pityriasis rosea, but oral erythromycin may be effective in treating the rash and decreasing the itch and both dexchlorpheniramine and betamethasone alone seem to be better at clearing rash.

Case reports and studies on pityriasis rosea – from number of patients to meta-analyses and diagnostic criteria

TLDR
A diagnostic criteria for typical and atypical PR is proposed and it is believed that the rash in this infant in concern fulfils all the three essential clinical features, and therefore can be meta-analysed and systematically reviewed with regard to aetiology, immunopathogenesis, and management strategies.

Efficacy of clarithromycin in pityriasis rosea.

TLDR
Clarithromycin is not effective in treatment of pityriasis rosea and should not be considered as a treatment option, according to the authors.

Human herpesvirus 6 and 7 DNA in peripheral blood leucocytes and plasma in patients with pityriasis rosea by polymerase chain reaction: a prospective case control study.

TLDR
It is found that there is no evidence of recent HHV-6 orHHV-7 infection in patients with a diagnosis of pityriasis rosea, and antibody to HHv-7 was found in all 15 of patients and controls.