Pityriacitrin – an ultraviolet-absorbing indole alkaloid from the yeast Malassezia furfur

  title={Pityriacitrin – an ultraviolet-absorbing indole alkaloid from the yeast Malassezia furfur},
  author={Peter Andreas Mayser and Ute Sch{\"a}fer and H. -J. Kr{\"a}mer and Bernhard Irlinger and Wolfgang Steglich},
  journal={Archives of Dermatological Research},
As the main nitrogen source in Malassezia furfur, tryptophan induces the formation of fluorochromes and pigments, which make the yeast less sensitive to UV light. To detect a chemical UV filter, M. furfur (CBS 1878) was incubated at 30ºC for 14 days on a pigment-inducing medium and agar extracts were purified by column chromatography, preparative TLC and HPLC. Structural analysis of the pure metabolites was performed by mass spectroscopy and NMR. A yellow compound eluting from the column with… CONTINUE READING


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