Pituitary volume in neuroleptic-naïve schizophrenia: a structural MRI study.

  title={Pituitary volume in neuroleptic-na{\"i}ve schizophrenia: a structural MRI study.},
  author={Ameet R Upadhyaya and Rhonda El-Sheikh and Frank P MacMaster and Vaibhav A. Diwadkar and Matcheri S. Keshavan},
  journal={Schizophrenia research},
  volume={90 1-3},
Abnormalities in the hypothalamic-pituitary-adrenal axis (HPA) have been implicated in psychosis. To our knowledge, no prior study has measured pituitary volume in a neuroleptic-naïve schizophrenic population. Herein, we present data exploring the volumetric differences in a sample of antipsychotic-naïve patients with a DSM-IV diagnosis of schizophrenia versus appropriately matched healthy controls. Pituitary volumes were measured in 51 patients with schizophrenia (36 males, 15 females, mean… CONTINUE READING

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