Pituitary hormones in brain: where, how, and why?


Peptide and protein hormones usually considered as being of pituitary origin have been detected within the central nervous system by means of radioimmunoassay, bioassay, and immunocytochemical techniques. Intracerebral administration of some of these hormones or fragments thereof elicit behavioral responses, suggesting that they may have a physiological role similar to that described for other peptidergic neurotransmitter or neuromodulator substances. Evidence available for some of these hormones indicates that they are synthesized within the central nervous system and that their regulation may differ from that of their pituitary counterparts.


Citations per Year

1,207 Citations

Semantic Scholar estimates that this publication has 1,207 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Krieger1979PituitaryHI, title={Pituitary hormones in brain: where, how, and why?}, author={Dorothy T Krieger and A. S. Liotta}, journal={Science}, year={1979}, volume={205 4404}, pages={366-72} }