Pituitary and autonomic responses to cold exposures in man.

  title={Pituitary and autonomic responses to cold exposures in man.},
  author={Juhani Lepp{\"a}luoto and Tiina M. P{\"a}{\"a}kk{\"o}nen and Ilkka Korhonen and Juhani Hassi},
  journal={Acta physiologica Scandinavica},
  volume={184 4},
This review presents hormonal responses to various cold exposures and their calorigenic effects in man and some animals. Previous studies in rats have shown that cold exposures activate the hypothalamic-pituitary-thyroid axis. Increased thyroid hormone concentrations lead to heat production via general stimulation of metabolism (obligatory thermogenesis) and possibly via activation of thyroid hormone receptors and uncoupling protein 1 (UCP 1) and deiodinase enzyme genes in the brown adipose… CONTINUE READING