Pituitary adenylate cyclase-activating polypeptide (PACAP) and islet function.

@article{Ahrn2010PituitaryAC,
  title={Pituitary adenylate cyclase-activating polypeptide (PACAP) and islet function.},
  author={Bo Ahr{\'e}n},
  journal={Regulatory peptides},
  year={2010},
  volume={164 1},
  pages={23}
}
In healthy subjects, the incretin effect ensures that plasma glucose concentrations after oral carbohydrates remain low regardless of the amount of glucose taken in. It is due to proportional increases in GLP-1 and GIP secretion and corresponding insulin responses We studied this phenomenon in obese subjects with T2DM and matched controls and found that… CONTINUE READING