Pituitary adenoma producing growth hormone and adrenocorticotropin: a histological, immunocytochemical, electron microscopic, and in situ hybridization study. Case report.

@article{Kovacs1998PituitaryAP,
  title={Pituitary adenoma producing growth hormone and adrenocorticotropin: a histological, immunocytochemical, electron microscopic, and in situ hybridization study. Case report.},
  author={Kalman T. Kovacs and Eva Horv{\'a}th and Lucia Stefaneanu and Juan Bilbao and William Singer and Paul J. Muller and Kamal Thapar and Edwin S Stone},
  journal={Journal of neurosurgery},
  year={1998},
  volume={88 6},
  pages={1111-5}
}
The authors report on the morphological features of a pituitary adenoma that produced growth hormone (GH) and adrenocorticotropic hormone (ACTH). This hormone combination produced by a single adenoma is extremely rare; a review of the available literature showed that only one previous case has been published. The tumor, which was removed from a 62-year-old man with acromegaly, was studied by histological and immunocytochemical analyses, transmission electron microscopy, immunoelectron… CONTINUE READING
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