Pitfalls in the quest of neuroprotectants for the perinatal brain.

Abstract

Sick preterm and term newborns are highly vulnerable to neural injury, and thus there has been a major search for new, safe and efficacious neuroprotective interventions in recent decades. Preclinical studies are essential to select candidate drugs for clinical trials in humans. This article focuses on 'negative' preclinical studies, i.e. studies where… (More)
DOI: 10.1159/000333109

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