Pitfalls in the current published observational literature on the effects of red blood cell storage.

@article{Watering2011PitfallsIT,
  title={Pitfalls in the current published observational literature on the effects of red blood cell storage.},
  author={L van de Watering},
  journal={Transfusion},
  year={2011},
  volume={51 8},
  pages={1847-54}
}
P ossible adverse effects related to transfusing “old” red blood cells (RBCs) have been investigated extensively. As the ongoing randomized controlled trials (RCTs) on the effects of RBC storage may still take years to report their results, current RBC storage and transfusion policies will have to be based on the currently available, mostly observational, literature. These observational studies are valuable, as they may rationally direct the formulation of sound hypotheses. However, the results… CONTINUE READING

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