Pirmenol: preclinical pharmacology.

  title={Pirmenol: preclinical pharmacology.},
  author={Harry Kaplan and Thomas E. Mertz and T J Steffe},
  volume={39 3 Pt 2},
Pirmenol, a novel pyridinemethanol derivative, is active in a variety of experimental arrhythmic models of diverse etiology. Animal pharmacology studies showed that pirmenol is highly efficacious whether the arrhythmias were atrial or ventricular in origin; chemically, mechanically, or electrically induced; or of the automaticity or reentrant types. The… CONTINUE READING