Pirenzepine prevents form deprivation myopia in a dose dependent manner.

@article{Leech1995PirenzepinePF,
  title={Pirenzepine prevents form deprivation myopia in a dose dependent manner.},
  author={Eleanor M. Leech and Charles L. Cottriall and Neville A. Mcbrien},
  journal={Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians},
  year={1995},
  volume={15 5},
  pages={351-6}
}
Previous studies have demonstrated that muscarinic antagonists, such as atropine and pirenzepine, block form deprivation myopia in avian and mammalian models. The aim of the present investigation was to establish dose-response curves for intravitreal and subconjunctivally injected pirenzepine and to determine receptor specificity. Chicks were monocularly deprived of form vision for five days and received daily injections of either pirenzepine or saline. Keratometry, retinoscopy and A-scan… CONTINUE READING

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