Piracetam in Alcoholic Psychoses: A Double-Blind, Crossover, Placebo Controlled Study

  title={Piracetam in Alcoholic Psychoses: A Double-Blind, Crossover, Placebo Controlled Study},
  author={V. Skondia and J. Kabe{\vs}},
  journal={Journal of International Medical Research},
  pages={185 - 187}
Introduction Various therapeutic approaches are applied for the treatment of psychiatric complications in patients suffering from chronic alcoholism, such as in the case of predeliriurn state, in delirium tremens and in alcoholic hallucinosis. One aim is to normalize the basic metabolic functions by means of the administration of infusions containing minerals, vitamins and glucose in order to rehydrate the patient, the other aim is a purely symptomatic treatment using tranquillizers and… Expand
Piracetam for dementia or cognitive impairment.
The evidence available from the published literature does not support the use of Piracetem in the treatment of people with dementia or cognitive impairment because effects were found only on global impression of change but not on any of the more specific measures. Expand
Therapeutic Applications of Citicoline and Piracetam as Fixed Dose Combination
Need for combination of citicoline and piracetam is highlighted, their pharmacological and therapeutic issues and application, for memory enhancement, neurological and cognitive disorder, Parkinsonism and Alzheimer disorder. Expand
Effects of piracetam on retention and biogenic amine turnover in albino rats
The results of this study implicate the involvement of NE, DA, and 5-HT systems in learning and memory processes and indicate that piracetam causes an overall decrease in the turnover of central monoamines. Expand
Chapter 4. Cognitive Disorders
This chapter briefly discusses the active research area, and then discusses the other chemotherapeutic approaches that show promise in the treatment of cognitive dysfunction. Expand
Recent development in 2‐pyrrolidinone‐containing nootropics
This paper reviews the development of the concept of nootropics‐‐compounds whose activity appears to be specific to enhancement and protection of those functions of plasticity of the central nervousExpand
High field NMR techniques and molecular modelling study of the inclusion complexes of the nootropic drug tenilsetam (CAS-997) in cyclodextrins
The inclusion complexes of the chiral anti-amnesic drug 3-(2-thienyl)piperazin-2-one (Tenilsetam, CAS-997) with α-, β- and γ-cyclodextrins (CDs) were studied by high resolution 1H NMR spectroscopyExpand
High‐field NMR techniques and molecular modelling in the study of the inclusion complex of the cognition activator suronacrine (HP‐128) with cyclodextrins
The structural features of the inclusion complexes of cyclodextrins (CDs) with the chiral cognition activator drug (±)9‐[(phenylmethyl)amino]‐1,2,3,4‐tetrahydroacridin‐1‐ol maleate (suronacrineExpand
Conformation of the nootropic agents 1-(4-methoxybenzoyl)-5-oxo-2-pyrrolidinepropanoic acid (CI-933) and 4-hydroxymethyl-1-benzyl-pyrrolidin-2-one (WEB-1868): X-ray crystal structures, theoretical MO calculations (AM-1) and 600 MHZ 1H NMR spectra
Abstract The crystal and molecular structures of the cognition activators 1-(4-methoxybenzoyl)-5-oxo-2-pyrrolidinepropanoic acid (CI-933) ( 1 ) and 4-hydroxymethyl-1-benzyl-pyrrolidin-2-oneExpand
. 3 ( 2 ) Method Development and Validation of RP-HPLC for Simultaneous Estimation of Citicoline and Piracetam in Tablet Dosage Form
Reverse Phase-High Performance Liquid Chromatography (RP-HPLC) method have been developed and validated for the estimation of Citicoline and Piracetam in Bulk drug and Pharmaceutical dosage form. TheExpand


[Course of alcoholic predelirium during treatment with piracetam: results of serial psychometric tests (author's transl)].
The degree of psychometrically determined abnormalities pointed to serious cerebral lesions even in the mild predelirial stage and exceeded the expectations gained from clinical impression. Expand
Verlauf des alkoholischen Pradelir unter der Behandlung mit Piracetam
  • Deutsch Medizinische Wochenschrift
  • 1979
Verlauf des alkoholischen Pradelir unter der Behandlung mit Piracetam
  • Deutsch Medizinische Wochenschrift
  • 1979
Le piracetam dans Ie traitement de l'alcoolisme aigu et chronique
  • Revue de Medecine de Tours 9,
  • 1975
Etude clinique et therapeutique de l'emploi du piracetam dans Ie delirium tremens
  • Wochenschrift
  • 1973
Perspectives therapeutiques du piracetam dans les etats de detresse cerebrale aigue
  • Proc, 69th Session of Congres Psych. Neurol. Langue Franc.,
  • 1971
Etude d ' orientation du piracetam dans I ' alcool - isme aigu et chronique
  • 1970