Pipradrol enhances reinforcing properties of stimuli paired with brain stimulation.

@article{Robbins1978PipradrolER,
  title={Pipradrol enhances reinforcing properties of stimuli paired with brain stimulation.},
  author={Trevor W. Robbins and George F. Koob},
  journal={Pharmacology, biochemistry, and behavior},
  year={1978},
  volume={8 3},
  pages={219-22}
}
The hypothesis that a psychomotor stimulant drug (pipradrol) enhances the reinforcing effects of stimuli paired with reinforcing brain stimulation was tested using a conditioned reinforcement paradigm. Rats were trained to discriminate between two stimuli (S+ and S-) to obtain ICS in the lateral hypothalamus by pushing a panel in the presence of S+. In a subsequent preference test, ICS was no longer available, but responding on one of two novel levers now produced S+, whereas responding on the… CONTINUE READING