PipX, the coactivator of NtcA, is a global regulator in cyanobacteria.

  title={PipX, the coactivator of NtcA, is a global regulator in cyanobacteria.},
  author={Javier Espinosa and Francisco Rodr{\'i}guez-Mateos and Paloma Salinas and Val F. Lanza and Ray Dixon and F Sebasti{\'a}n de la Cruz and Asunci{\'o}n Contreras},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={111 23},
To modulate the expression of genes involved in nitrogen assimilation, the cyanobacterial PII-interacting protein X (PipX) interacts with the global transcriptional regulator NtcA and the signal transduction protein PII, a protein found in all three domains of life as an integrator of signals of the nitrogen and carbon balance. PipX can form alternate complexes with NtcA and PII, and these interactions are stimulated and inhibited, respectively, by 2-oxoglutarate, providing a mechanistic link… CONTINUE READING


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Cluster Analysis Basics and Extensions. R package version 1.15.2

  • M Maechler, P Rousseeuw, A Struyf, M Hubert, K Hornik
  • Available at http://cran.stat.ucla.edu/web…
  • 2014
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