Pioglitazone significantly prevented decreased rate of neural differentiation of mouse embryonic stem cells which was reduced by Pex11β knock-down.

@article{Esmaeili2016PioglitazoneSP,
  title={Pioglitazone significantly prevented decreased rate of neural differentiation of mouse embryonic stem cells which was reduced by Pex11β knock-down.},
  author={Maryam Esmaeili and Kamran Ghaedi and Alireza Shoaraye Nejati and Marzieh Nematollahi and H Shiralyian and Mohammad Hossein Nasr-esfahani},
  journal={Neuroscience},
  year={2016},
  volume={312},
  pages={35-47}
}
Peroxisomes constitute special cellular organelles which display a variety of metabolic functions including fatty acid oxidation and free radical elimination. Abundance of these flexible organelles varies in response to different environmental stimuli. It has been demonstrated that PEX11β, a peroxisomal membrane elongation factor, is involved in the regulation of size, shape and number of peroxisomes. To investigate the role of PEX11β in neural differentiation of mouse embryonic stem cells… CONTINUE READING

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