Pioglitazone reduces urinary podocyte excretion in type 2 diabetes patients with microalbuminuria.

@article{Nakamura2001PioglitazoneRU,
  title={Pioglitazone reduces urinary podocyte excretion in type 2 diabetes patients with microalbuminuria.},
  author={Tsukasa Nakamura and Chifuyu Ushiyama and Shiwori Osada and Masanori Hara and Noriaki Shimada and Hikaru Koide},
  journal={Metabolism: clinical and experimental},
  year={2001},
  volume={50 10},
  pages={1193-6}
}
In various renal diseases, including diabetic nephropathy, detection of podocytes in the urine indicates severe injury to podocytes in the glomeruli. Pioglitazone is a newly developed antidiabetic agent that attenuates insulin resistance. The aim of the present study was to determine whether pioglitazone affects urinary albumin excretion (UAE) or the number of urinary podocytes or both in type 2 diabetes patients with microalbuminuria. Twenty-eight patients with normotensive type 2 diabetes and… CONTINUE READING

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