Pioglitazone initiation and subsequent hospitalization for congestive heart failure.

@article{Karter2005PioglitazoneIA,
  title={Pioglitazone initiation and subsequent hospitalization for congestive heart failure.},
  author={Andrew J. Karter and Ahmed T. Ahmed and J Liu and Howard H. Moffet and Melissa M. Parker},
  journal={Diabetic medicine : a journal of the British Diabetic Association},
  year={2005},
  volume={22 8},
  pages={986-93}
}
AIMS Thiazolidinediones (TZD) have been associated with an expansion in plasma volume and the development of peripheral oedema. A recent study reported an association between the use of TZDs and development of congestive heart failure (CHF). The objective of this study was to determine if short-term use of pioglitazone, a TZD, is associated with increased risk of admission to hospital because of CHF in a well-characterized, community-based cohort of Type 2 diabetic patients without prevalent… CONTINUE READING