Pioglitazone improves endothelial function with increased adiponectin and high-density lipoprotein cholesterol levels in type 2 diabetes.

@article{Tsuchiya2009PioglitazoneIE,
  title={Pioglitazone improves endothelial function with increased adiponectin and high-density lipoprotein cholesterol levels in type 2 diabetes.},
  author={Kyoichiro Tsuchiya and Itaru Akaza and Takanobu Yoshimoto and Yukio Hirata},
  journal={Endocrine journal},
  year={2009},
  volume={56 5},
  pages={691-8}
}
Endothelial dysfunction is considered to be an early event in the development of atherosclerosis. The present study was undertaken to evaluate endothelial function and biochemical markers in type 2 diabetes mellitus (T2DM) patients before and after treatment with or without pioglitazone (PIO). Forty-one T2DM patients without macroangiopathy were randomized… CONTINUE READING