Pioglitazone and bladder cancer: a propensity score matched cohort study.

  title={Pioglitazone and bladder cancer: a propensity score matched cohort study.},
  author={Li Wei and Thomas M. MacDonald and Isla S Mackenzie},
  journal={British journal of clinical pharmacology},
  volume={75 1},
AIM To examine whether exposure to pioglitazone use is associated with increased incidence of bladder cancer in patients with type 2 diabetes mellitus. METHOD A cohort study was done in the General Practice Research Database (GPRD) between 2001 and 2010. Two hundred and seven thousand seven hundred and fourteen patients aged ≥40 years with type 2 diabetes were studied (23,548 exposed to pioglitazone and 184,166 exposed to other antidiabetic medications but not pioglitazone). The association… CONTINUE READING
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