Pioglitazone, a peroxisome proliferator-activated receptor gamma activator, ameliorates experimental autoimmune myocarditis by modulating Th1/Th2 balance.

@article{Hasegawa2005PioglitazoneAP,
  title={Pioglitazone, a peroxisome proliferator-activated receptor gamma activator, ameliorates experimental autoimmune myocarditis by modulating Th1/Th2 balance.},
  author={Hiroshi Hasegawa and Hiroyuki Takano and Yun-zeng Zou and Yingjie Qin and Kaoru Hizukuri and Kenichi Odaka and Tetsuya Toyozaki and Issei Komuro},
  journal={Journal of molecular and cellular cardiology},
  year={2005},
  volume={38 2},
  pages={257-65}
}
OBJECTIVES The aim of this study is to investigate the effect of Peroxisome proliferator-activated receptor gamma (PPAR gamma) ligand on experimental autoimmune myocarditis (EAM). BACKGROUND Rat EAM model resembles the giant cell myocarditis in human. Recent studies have suggested that Th1 cytokines are involved in the initiation and progression of EAM… CONTINUE READING