Pinocembrin protects against b-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products ( RAGE )-independent signaling pathways and regulating mitochondrion-mediated apoptosis

@inproceedings{Liu2012PinocembrinPA,
  title={Pinocembrin protects against b-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products ( RAGE )-independent signaling pathways and regulating mitochondrion-mediated apoptosis},
  author={Rui Liu and Cai-xia Wu and Dan Zhou and Fan Yang and Shuo Tian and Li Zhang and Tian-tai Zhang and Guan-hua Du},
  year={2012}
}
Background: It is known that amyloid-b peptide (Ab) plays a pivotal role in the pathogenesis of Alzheimer’s disease (AD). Interaction between Ab and the receptor for advanced glycation end products (RAGE) has been implicated in neuronal degeneration associated with this disease. Pinocembrin, a flavonoid abundant in propolis, has been reported to possess… CONTINUE READING