Pinocchio cells: morphologically atypical immunologically heterogeneous lymphocytes induced by treatment with interleukin 2.

@article{Paciucci1988PinocchioCM,
  title={Pinocchio cells: morphologically atypical immunologically heterogeneous lymphocytes induced by treatment with interleukin 2.},
  author={Paolo Alberto Paciucci and P G Chesa and Mar{\'i}a T Fierro and Rebecca Gordon and R G Konefal and O J Glidewell and James F. Holland},
  journal={Immunology letters},
  year={1988},
  volume={19 4},
  pages={313-20}
}
We describe a novel cell type, the Pinocchio cell, that appears in the peripheral blood of all patients receiving treatment with interleukin 2, up to 20,000 cells/microliter. This cell is characterized by a prominent and granular proboscis with which it attaches to tumor cells and mediates tumor cell lysis. Pinocchio cells are immunologically heterogeneous… CONTINUE READING