Pinnisterols A–C, New 9,11-Secosterols from a Gorgonian Pinnigorgia sp.

  title={Pinnisterols A–C, New 9,11-Secosterols from a Gorgonian Pinnigorgia sp.},
  author={Yu-Chia Chang and Liang-Mou Kuo and Tsong-Long Hwang and Jessica Yeh and Zhi-Hong Wen and Lee-shing Fang and Yang-Chang Wu and Chan-Shing Lin and J H Sheu and Ping-Jyun Sung},
  journal={Marine Drugs},
Three new 9,11-secosterols, pinnisterols A–C (1–3), were isolated from a gorgonian coral Pinnigorgia sp., collected off the waters of Taiwan. The structures of these compounds were elucidated on the basis of spectroscopic methods. The new sterols 1 and 3 displayed significant inhibitory effects on the generation of superoxide anions and the release of elastase by human neutrophils, and sterol 1 was found to show moderate cytotoxicity in hepatic stellate cells (HSCs). 
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