Pinellia ternata agglutinin produced in Bombyx mori cells exhibits bioactivity.

  title={Pinellia ternata agglutinin produced in Bombyx mori cells exhibits bioactivity.},
  author={Tao Xu and Bo Wang and Liya Wang and Yaozhou Zhang and Zhengbing Lv},
  journal={Acta biochimica Polonica},
  volume={59 2},
Pinellia ternata agglutinin (PTA) is highly homologous to many other monocot mannose-binding lectins which reportedly possess antitumor activities. Its production in silkworm cells has great application potential because the baculovirus expression system can produce post-translationally modified proteins at low cost. In the current study, the pta gene was cloned and expressed in silkworm cells, and the expressed protein was analyzed using a hemagglutination assay. A preliminary in vitro study… CONTINUE READING


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