Pineal gene expression: dawn in a dark matter.

@article{Stehle1995PinealGE,
  title={Pineal gene expression: dawn in a dark matter.},
  author={J{\"o}rg H. Stehle},
  journal={Journal of pineal research},
  year={1995},
  volume={18 4},
  pages={
          179-90
        }
}
The mammalian pineal gland serves as a neuroendocrine interface to convert environmental lighting conditions into a humoral message, the nocturnally elevated synthesis of melatonin. Regulation and fine tuning of the circadian melatonin production in response to external cues requires complex interactions of transsynaptic signalling. These requirements are fulfilled by a high degree of plasticity on all levels between receptor activation and cellular response. Many receptors on pinealocytic… CONTINUE READING
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