Pindolol augmentation in aggressive schizophrenic patients: a double-blind crossover randomized study

@article{Caspi2001PindololAI,
  title={Pindolol augmentation in aggressive schizophrenic patients: a double-blind crossover randomized study},
  author={N. Caspi and I. Modai and P. Barak and A. Waisbourd and H. Zbarsky and S. Hirschmann and M. Ritsner},
  journal={International Clinical Psychopharmacology},
  year={2001},
  volume={16},
  pages={111-115}
}
  • N. Caspi, I. Modai, +4 authors M. Ritsner
  • Published 2001
  • Psychology, Medicine
  • International Clinical Psychopharmacology
  • Treatment of aggression in schizophrenic patients is a major challenge. We sought to examine the efficacy of augmentation of antipsychotic treatment with pindolol in the amelioration of aggression. Thirty male inpatients meeting DSM-IV criteria for schizophrenia, aged 20-65 years involved in four or more aggressive incidents in the two previous months, were enrolled in a double-blind crossover study. Aggression was evaluated per incident, with the Overt Aggression Scale (OAS). Positive and… CONTINUE READING
    47 Citations

    Topics from this paper

    Fluvoxamine as an adjunctive agent in schizophrenia.
    • H. Silver
    • Psychology, Medicine
    • CNS drug reviews
    • 2001
    • 42
    • PDF
    Treatment of acute agitation in psychotic disorders.
    • 41
    • PDF
    Pharmacological management of persistent hostility and aggression in persons with schizophrenia spectrum disorders: a systematic review.
    • 34
    The Psychopharmacology of Aggressive Behavior: A Translational Approach Part 1 Neurobiology
    • 96
    Beta-blocker supplementation of standard drug treatment for schizophrenia.
    • 23
    The psychopharmacology of violence: making sensible decisions
    • 41

    References

    SHOWING 1-10 OF 28 REFERENCES
    Can aggressive behavior in humans be modified by beta blockers?
    • 12
    Serotonergic function in aggressive and nonaggressive boys with attention deficit hyperactivity disorder.
    • 149
    Serotonin uptake by platelets of suicidal and aggressive adolescent psychiatric inpatients.
    • 49
    The positive and negative syndrome scale (PANSS) for schizophrenia.
    • 15,643
    • Highly Influential
    • PDF
    Impulsive aggression and central serotonergic system function in humans: an example of a dimensional brain‐behavior relationship
    • E. Coccaro
    • Psychology, Medicine
    • International clinical psychopharmacology
    • 1992
    • 220
    The current state of psychiatry in the treatment of violent patients.
    • K. Tardiff
    • Medicine
    • Archives of general psychiatry
    • 1992
    • 120
    Beta-adrenergic blockers for the control of aggressive behaviors in patients with chronic schizophrenia.
    • 58