Pindolol augmentation in aggressive schizophrenic patients: a double-blind crossover randomized study

  title={Pindolol augmentation in aggressive schizophrenic patients: a double-blind crossover randomized study},
  author={N. Caspi and I. Modai and P. Barak and A. Waisbourd and H. Zbarsky and S. Hirschmann and M. Ritsner},
  journal={International Clinical Psychopharmacology},
  • N. Caspi, I. Modai, +4 authors M. Ritsner
  • Published 2001
  • Psychology, Medicine
  • International Clinical Psychopharmacology
  • Treatment of aggression in schizophrenic patients is a major challenge. We sought to examine the efficacy of augmentation of antipsychotic treatment with pindolol in the amelioration of aggression. Thirty male inpatients meeting DSM-IV criteria for schizophrenia, aged 20-65 years involved in four or more aggressive incidents in the two previous months, were enrolled in a double-blind crossover study. Aggression was evaluated per incident, with the Overt Aggression Scale (OAS). Positive and… CONTINUE READING
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