Pin1 overexpression in colorectal cancer and its correlation with aberrant beta-catenin expression.

@article{Kim2005Pin1OI,
  title={Pin1 overexpression in colorectal cancer and its correlation with aberrant beta-catenin expression.},
  author={Chang-Jae Kim and Yong-Gu Cho and Yong Gyu Park and Suk-Woo Nam and Su-Young Kim and Sug Hyung Lee and Nam-Jin Yoo and Jung-Young Lee and W Park},
  journal={World journal of gastroenterology},
  year={2005},
  volume={11 32},
  pages={5006-9}
}
AIM To investigate clinical significance of Pin1 and beta-catenin expression in colorectal cancers and to demonstrate the relationship of their expression. METHODS The role of Pin1 and beta-catenin protein in colorectal tumorigenesis and their clinicopathologic significance were analyzed by immunohistochemistry, and the correlation between Pin1 and beta-catenin protein expressions was also studied in 124 patients with colorectal cancer who were surgically treated. RESULTS Normal colonic… CONTINUE READING