Pimozide combined with behavior therapy in the short‐term treatment of anorexia nervosa

@article{Vandereycken1982PimozideCW,
  title={Pimozide combined with behavior therapy in the short‐term treatment of anorexia nervosa},
  author={Walter Vandereycken and Roland A. Pierloot},
  journal={Acta Psychiatrica Scandinavica},
  year={1982},
  volume={66}
}
Eighteen female inpatients were included in a double‐blind placebo‐controlled cross‐over study aimed at testing the hypothesis that dopamine blockade may enhance the effectiveness of behavior therapy in the short‐term weight restoration of anorexia nervosa patients. The patients were given a uniform contingency management program and, after a baseline period, they alternatingly (3‐ week periods) received pirnozide (4 or 6 mg) or a placebo. During the first two periods pimozide almost… 
Neuroleptics in the short-term treatment of anorexia nervosa. A double-blind placebo-controlled study with sulpiride.
  • W. Vandereycken
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    The British journal of psychiatry : the journal of mental science
  • 1984
There is a remarkable lack of controlled investigations about the usefulness of psychotropic drugs in anorexia nervosa despite the popular use of neuroleptics in these patients. Inspired by a
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TLDR
Given the overall trend toward improvement that was observed, quetiapine appears to be a promising candidate for the treatment of anorexia nervosa, and further large-scale placebo-controlled clinical trials will be necessary to fully evaluate the benefits of quet iapine treatment for this disorder.
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TLDR
There was a differential drug effect present in the bulimic subgroups of the anorectic patients: cyproheptadine significantly increased treatment efficiency for the nonbulimic patients and significantly impaired treatment efficiency when compared with the amitriptyline- and placebo-treated groups.
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This paper reviews behavioural and cognitive-behavioural treatments of anorexia nervosa, bulimia nervosa, and obesity. For anorexia and bulimia a review is attempted of controlled trials with a cell
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TLDR
It is hoped that over time, with reduced cultural pressures to diet and with more emphasis on early detection of those individuals at risk of developing eating disorders, the occurrence and complications of these disorders will be reduced.
Reports of Olanzapine Treatment of Anorexia Nervosa
Two females with severe anorexia nervosa were treated with olanzapine in open trials. Olanzapine was tried because it has caused weight gain in other patient groups. Both anorexic patients had a
Pharmacologic Approaches in the Treatment of Eating Disorders
TLDR
This review focuses primarily on summarizing results of published controlled trials of pharmacotherapy in patients with bulimia nervosa, and outlines the more limited literature on controlled pharmacotherapy trials for anorexia nervosa and for the provisionally identified syndrome of binge eating disorder.
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