Pimavanserin tartrate: a 5-HT2A inverse agonist with potential for treating various neuropsychiatric disorders
@article{Abbas2008PimavanserinTA, title={Pimavanserin tartrate: a 5-HT2A inverse agonist with potential for treating various neuropsychiatric disorders}, author={Atheir I. Abbas and Bryan L. Roth}, journal={Expert Opinion on Pharmacotherapy}, year={2008}, volume={9}, pages={3251 - 3259} }
Background: Pimavanserin tartrate is the first 5-HT2A inverse agonist to enter clinical trials as a treatment for L-dopa-induced psychosis in Parkinson's disease and for augmentation of low-dose risperidone treatment in schizophrenia. Pimavanserin is also being evaluated as a possible anti-insomnia drug. Objective: To discuss the potential of pimavanserin to fill multiple therapeutic needs. Methods: The problems with currently approved antipsychotics and sleep agents are explored to highlight…
33 Citations
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